NHIA's Quick Coding References for Home Infusion Therapy

Thanks to the support from Acu-Serve, the following references are available as NHIA member-only benefits.

  • 2026 Guide for Billing S-codes for HIT to Non-Medicare Payers
  • 2026 Guide for Billing Medicare Part B for Home Infusion Therapy Services
  • 2026 Guide for Billing Medicare Equipment and Supply Codes

2026 Guide for Billing S-codes for HIT to Non-Medicare Payers (2026PDQCR)

Per HIPAA regulation, providers and payers must use national standard codes and conform to HCPCS and CPT® code descriptions which may not be changed. HCPCS per diem S-codes have descriptions which (1) specify what is included in payment for the code and (2) by exclusion specify what is coded, billed, and paid for separately.

2026 Guide for Billing Medicare Part B for Home Infusion Therapy Services (2026HITQCR)

The Medicare Part B HIT Services is very limited in scope, applying only to a subset of the DME infused drugs covered under the external infusion pump benefit (see below). While both are Part B benefits, the HIT services benefit is separate from the DMEPOS benefit, requiring different accreditation, enrollment, documentation, and billing procedures.

2026 Guide for Billing Medicare Equipment and Supply Codes (2025ESQCR)

Per HIPAA regulation, providers and payers must use national standard codes and conform to HCPCS and CPT® code descriptions which may not be changed. While most infusion claims are billed with HCPCS per diem S-codes, others need to be billed using supply and equipment codes.

NHIA Summary of Medicare Changes cover image

2026 Summary of 2026 Medicare Changes

Additional Coding References

Download the COVID-19 Treatment Billing, Coding & Enrollment Resource

The Centers for Medicare & Medicaid Services (CMS) has cast a wide net regarding which entities can provide
and bill for COVID-19 treatments. The list includes pharmacies enrolled with the A/B MAC (to provide factor
products) and pharmacies enrolled in the durable medical equipment, prosthetics, orthotics and supplies
(DMEPOS) program.

Learn how to enroll and bill for COVID-19 treatments.